PGD in IVF: Costs, Benefits, and Is It the Right Choice for You?

When planning a family through IVF, many couples are introduced to the option of Preimplantation Genetic Diagnosis (PGD). PGD is a laboratory procedure that screens embryos for genetic conditions before they are implanted in the uterus. For couples with a history of genetic disorders, recurrent miscarriages, or advanced maternal age, PGD can offer valuable peace of mind.

However, the two most common questions couples ask are: How much does PGD cost? And is it worth the investment? This blog will explore what PGD involves, its costs in India and worldwide, and whether it could be the right choice for your family planning journey.

What Is PGD and When Is It Recommended?

PGD is an advanced form of embryo testing carried out during IVF. After eggs are fertilised in the laboratory, embryos are allowed to grow for a few days. At the blastocyst stage, a few cells are gently removed from each embryo and analysed for specific genetic conditions. Only healthy embryos are then selected for transfer to the uterus.

PGD is typically recommended when:

• One or both parents carry a known genetic condition.
• There is a family history of genetic illness.
• A couple has experienced recurrent miscarriages.
• The mother is of advanced maternal age and at higher risk of chromosomal abnormalities.

It is essential to note that PGD differs from PGS/PGT-A (Preimplantation Genetic Screening). PGD identifies specific inherited genetic diseases, whereas PGS screens embryos for chromosomal abnormalities without targeting particular conditions.

Average Cost of PGD in India and Internationally

The cost of PGD in India generally ranges from ₹2.5 to ₹5 lakhs, depending on the clinic, the number of embryos tested, and the type of genetic analysis used. This cost is in addition to IVF expenses, which themselves range between ₹1.5 and ₹2.5 lakhs per cycle.

Internationally, PGD costs are higher. In the United States and the UK, the average range is $4,000 to $7,500 per cycle, which is typically added to IVF costs.

Factors that influence PGD pricing include:

• The number of embryos undergoing biopsy and testing.
• The technology used (Next-Generation Sequencing, FISH, or array CGH).
• The level of expertise and laboratory infrastructure at the clinic.

For couples in India, PGD provides access to advanced genetic testing at a more affordable cost compared to many Western countries, while still requiring significant financial planning.

What Does the PGD Cost Cover?

The cost of PGD includes several procedures and services that extend beyond the IVF cycle itself. These typically cover:

• Embryo biopsy: A highly skilled embryologist removes cells for testing.
• Genetic testing and lab analysis: DNA analysis of the embryo to detect genetic abnormalities.
• Embryo freezing and storage: Healthy embryos may be frozen and stored for later transfer.
• Embryo transfer procedure: Implantation of selected embryos into the uterus.
• Specialist consultation and genetic counselling: Guidance from fertility specialists and genetic counsellors to interpret results and decide next steps.

This combination ensures that couples receive not just the test results but also professional support in making informed decisions.

Key Factors Affecting PGD Cost

Several elements can influence the overall cost of PGD:

1. Clinic reputation and location: Premium centres in metropolitan areas often charge more but provide advanced technology and higher success rates.
2. Type of genetic testing required: Single-gene mutation testing is less costly than complete chromosomal analysis.
3. Number of embryos tested: More embryos mean higher costs.
4. Additional IVF procedures: Use of ICSI (Intracytoplasmic Sperm Injection) or extended embryo freezing adds to the expense.
5. Repeated cycles: If the first round is unsuccessful, costs rise with subsequent attempts.

Couples should discuss all these factors with their fertility specialist before deciding on PGD to ensure clarity on financial planning.

Is PGD Worth the Investment?

Whether PGD is “worth it” depends on individual circumstances.

Benefits of PGD:

• Reduces the risk of passing on genetic disorders to children.
• Improves chances of a healthy pregnancy by identifying embryos free of abnormalities.
• Saves emotional and financial strain linked to recurrent miscarriages or managing genetic illness after birth.

When PGD may not be necessary:

• Couples without a family history of genetic disorders.
• Younger women with good fertility health have higher chances of producing healthy embryos.

For many couples, PGD is less about cost and more about peace of mind. By reducing uncertainty and increasing the chances of having a healthy baby, PGD is often viewed as an investment in family planning and future well-being.

In Conclusion

The average cost of PGD in India ranges from ₹2.5 to ₹5 lakhs, while international fees can be significantly higher. Deciding whether PGD is worth the expense depends on your medical history, emotional readiness, and financial considerations. For couples at higher risk of genetic conditions or recurrent pregnancy loss, PGD can be a valuable tool that not only improves the chances of success in IVF but also provides reassurance during the journey to parenthood. Consulting with an experienced fertility specialist is the best way to decide if PGD is right for you.

Expert Guidance on PGD and IVF

Considering PGD as part of your IVF journey? Dr. Nandita P. Palshetkar, one of Mumbai’s leading fertility specialists, provides expert advice and personalised treatment plans for couples exploring advanced reproductive options. Book a consultation today to understand whether PGD is right for you and take a confident step toward building your family.

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