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Having a child is one of life’s greatest joys. However, for many couples today, fertility challenges can make that journey more difficult. Intrauterine Insemination (IUI) offers hope, a simple, safe, and effective fertility treatment that increases the chances of conception by bringing sperm and egg closer together at the right time.
This guide will help you understand what IUI is, how it works, its advantages, and when it may be the right option for you.
Intrauterine Insemination (IUI) is a fertility treatment that involves placing specially prepared sperm directly into a woman’s uterus around the time of ovulation. This increases the likelihood of the sperm reaching and fertilising the egg naturally.
The process is typically performed by a qualified fertility specialist. The steps include:
Ovulation-stimulating medication to ensure egg maturity.
Monitoring follicle development through ultrasound and hormone testing.
Timing the insemination 24–36 hours after the LH surge (the hormone that triggers ovulation).
Washing and concentrating the sperm sample before it is gently introduced into the uterus using a thin catheter.
The procedure is quick, relatively painless, and completed within minutes.
Before the IUI procedure, your fertility specialist will review your medical history and perform diagnostic tests to assess the uterus and fallopian tubes.
Once ovulation is confirmed, your partner provides a sperm sample (or donor sperm is used if necessary). The sperm is processed in a laboratory to select the healthiest sperm. During the insemination, a small speculum is inserted to access the cervix, and the prepared sperm is introduced into the uterus through a narrow catheter.
The procedure resembles a Pap smear and causes little to no discomfort. Most women resume normal activities the same day.
After IUI, it’s natural to feel eager to know the outcome. Generally, a pregnancy test is recommended around 14 days after the procedure. This timeframe allows the embryo (if fertilisation occurs) to implant and produce detectable levels of the pregnancy hormone hCG.
Testing too early may lead to false negatives, so waiting the full two weeks is advisable for accurate results.
IUI is one of the most commonly recommended fertility treatments because it is both effective and less invasive than other options like IVF.
Here are the key advantages:
Minimally Invasive: The procedure does not require surgery or anaesthesia.
Cost-Effective: It is significantly less expensive than IVF, making it more accessible to many couples.
Natural Conception Process: IUI mimics natural fertilisation, helping sperm meet the egg inside the body.
Quick Recovery: The process is brief, with minimal downtime.
Flexible Treatment Options: IUI can be combined with ovulation-inducing medications or donor sperm for higher chances of success.
Lower Risk of Multiple Pregnancies: Compared with IVF, the risk of multiple gestations is lower, reducing pregnancy complications.
Emotional Comfort: Because it’s less invasive and shorter in duration, IUI offers a calmer and less stressful experience for many couples beginning their fertility journey.
While IUI offers an excellent first step toward conception, its success depends on several biological and lifestyle factors. Understanding these can help patients set realistic expectations.
Age: Fertility naturally declines with age. Women under 35 generally have higher IUI success rates.
Egg and Sperm Quality: Healthy eggs and sperm improve fertilisation chances significantly.
Timing: Accurately tracking ovulation ensures the sperm is placed at the optimal time for fertilisation.
Underlying Conditions: Factors like endometriosis, PCOS, or blocked fallopian tubes may reduce success rates, and your doctor may recommend additional treatments.
Lifestyle Choices: Maintaining a healthy weight, eating a nutrient-rich diet, avoiding smoking or alcohol, and managing stress can positively affect fertility outcomes.
Your fertility specialist will evaluate these factors and recommend whether IUI is suitable or if other options, such as IVF or ICS,I might offer higher success potential.
IUI is suitable for couples where natural conception has been difficult due to certain medical or lifestyle factors. Your fertility specialist may suggest IUI in cases such as:
Unexplained infertility
Mild endometriosis
Cervical or mucus-related issues
Low sperm count or motility
Ejaculation or erection problems
Single women or same-sex couples planning pregnancy
Couples wishing to use donor sperm
IUI is one of the most affordable fertility treatments available in India. The average cost ranges between ₹10,000 and ₹30,000 per cycle, depending on:
The woman’s age and health condition
The number of cycles required
Medication used for ovulation induction
The fertility clinic’s facilities and expertise
Your doctor will advise he number of cycles and protocols best suited to your situation.
For many couples, IUI is an encouraging first step in their fertility journey. It offers a balance between simplicity, affordability, and effectiveness. However, success rates depend on factors like age, the underlying cause of infertility, and overall reproductive health.
If you are considering fertility treatment, remember that every couple’s journey is different. A consultation with an experienced fertility expert can help you determine whether IUI or another assisted reproductive technique is right for you.
If you’re considering IUI treatment and want expert guidance from one of the best IVF doctors in Mumbai, book your consultation with Dr Nandita P. Palshetkar today. With over 35 years of experience and thousands of success stories, she is among the most trusted fertility specialists in India. She provides personalised treatment plans designed to improve your chances of conception.
Q1: How do I know my IUI is successful?
The first sign of success is usually a missed period followed by a positive pregnancy test taken about two weeks after the IUI procedure. Some women may also experience mild cramping or breast tenderness as early pregnancy symptoms.
Q2: How to make sure IUI is successful?
To improve your chances, follow your doctor’s advice on medication, timing, and lifestyle. Eating a healthy diet, managing stress, maintaining a healthy weight, and avoiding smoking or alcohol can positively influence IUI success.
Q3: What cycle of IUI is most successful?
IUI success rates typically increase over multiple cycles. Most pregnancies occur within the first three to six cycles. If pregnancy hasn’t occurred after several attempts, your doctor may suggest exploring other options like IVF.
Q4: How successful is IUI on the first try?
The success rate of IUI on the first attempt generally ranges between 10% and 20%, depending on age, egg quality, sperm motility, and any underlying fertility issues.
Q5: What to do immediately after IUI?
After IUI, rest for 15–30 minutes at the clinic and then continue your normal routine. Avoid strenuous activity, heavy lifting, and stress. Most importantly, follow all prescribed medications and attend follow-up appointments as advised.
